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Karlsruhe Institute of Technology - KIT
Institute for Applied Biosciences
Department of Microbiology


Fritz-Haber-Weg 4

Geb. 30.43, 3. OG

D-76187 Karlsruhe


Phone:  +49 721 608-44630

Secret.: +49 721 608-44632

Fax:      +49 721 608-44509



reinhard fischerWpf8∂kit edu


Yu et al. 2016

Takeshita et al. 2014



Rodriguez and Fischer 2012



Zekert and Fischer 2009



Xiang and Fischer 2004



Wei et al. 2001



Schier et al. 2001



Suelmann and Fischer 1997



Karos and Fischer 1996



Fischer and Timberlake 1995



130. Fischer, R. & Riquelme, M. (2017) Mycology: Unraveling the riddle of the filamentous fungi. 

ResearchFeatures., 109:18-21. pdf


129. Takeshita, N., Evangelinos, M., Zhou, L., Somera-Fajardo, R.A., Lu, L., Takaya, N., Nienhaus, G.U. & Fischer, R. (2017) Pulses of Ca2+ coordinate actin assembly and exocytosis for stepwise cell extension. 

Proc. Natl. Acad. Sci., 114:5701-5706 pdf


128. Wenderoth, M., Pinecker, C., Voß, B. & Fischer, R. (2017) Establishment of CRISPR/Cas9 in Alternaria alternata. 

Fungal Genet. Biol., 101:55-60. pdf


127. Zhang, Y., Gao, X. Manck, R. Schmid, M., Osmani, A.H., Osmani, S.A., Takeshita, N. & Fischer, R. (2017) Microbutule-organizing centers of Aspergillus nidulans are anchored at septa by a disordered protein.

Mol. Microbiol., in press.


126. Jiang, P., Wei, W., Zhong, G., Zhou, X., Qiao, W., Fischer, R., Lu, L. (2017) The function of the three phosphoribosyl-pyrophosphate synthetase (prs) genes in hyphal growth and conidiation in Aspergillus nidulans.

Microbiology, 163(2): 218-232. pdf


125. Röhrig, J., Yu, Zhenzhong, Chae, K.-S., Kim, J.-H., Han, K.-H. & Fischer, R. (2017) The Aspergillus nidulans Velvet-interacting protein, VipA, regulates light-dependent heme biosynthesis.

Mol. Microbiol., in press. pdf


124. de Vries, R.P., et al. (2017) Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus.

Genome Biol., 18:28.  pdf




123. Fokina, O., Fenchel, A., Winandy, L. & Fischer, R. (2016) Immobilizaton of LccC laccase from Aspergillus nidulans on hard surfaces using fungal hydrophobins.

Appl. Environ. Microbiol., 82(21): 6395-6402. pdf


122. Fokina, O., Eipper, J., Kerzenmacher, S. & Fischer, R. (2016) Characterization of secreted laccases of Pleurotus sajor-caju and their application at a biofuel cell cathode.

Biores. Technol., 218: 455-462. pdf


121. Fischer, R., Aguirre, J., Herrera-Estrella, A. & Corrochano, L.M. (2016) The complexity of fungal vision. in The Fungal Kingdom, Eds. Heitman, J., Howlett, B., Crous, P., Stukenbrock, E., James, T. & Gow, N., ASM Press., in press.

doi:10.1128/microbiolspec.FUNK-0020-2016.  pdf


120. Dempwolff, F., Schmidt, F.K., Hervás, A.B., Stroh, A., Rösch, T., Riese, C.N., Dersch, S., Heimerl, T., Cavalcanti de Lucena, D., Hülsbusch, N., Stürmer, C.A.O., Takeshita, N., Fischer, R., Eckhardt, B. & Graumann, P.L. (2016) Super resolution fluorescence microscopy and tracking of bacterial flotillin (reggie) paralogs provide evidence for defined-sized protein microdomains within the bacterial membrane but absence of clusters containing detergent-resistant proteins.

PLoS Genetics, 1006116, pdf


119. Yu, Z., Armant, O. & Fischer, R. (2016) Fungi use the SakA/HogA pathway for phytochrome-dependent light signaling.

Nature Microbiol., 2016, 1: 16019.   pdf 

Highlight in Nature Microbiol. Rev., 2016, 19: 192-193.  pdf 

News and Views in Nature Microbiol:pdf


118. Zhang, Y., Teichert, I., Kück, U. & Fischer, R. (2016) Laser capture microdissection to identify septum-associated proteins in Aspergillus nidulans.

Mycologia, 108(3): 528-532. pdf


117. Takeshita, N. & Fischer, R. (2016) The cytoskeleton and cell-end markers during polarized growth of filamentous fungi.

The Mycota, in press. 


116. Rauscher, S., Pacher, S., Kniemeyer, O. & Fischer, R. (2016) A phosphorylation code of the Aspergillus nidulans global regulator VelvetA (VeA) determines specific functions.

Mol. Microbiol., 99:909-924. pdf





115. Hedtke, M., Rauscher, S., Röhrig ,J., Rodriguez, J., Yu, Z., & Fischer, R. (2015) Light-dependent gene activation in Aspergillus nidulans is strictly dependent on phytochrome and involves the interplay of phytochrome and white-collar-regulated histone H3 acetylation.

Mol. Microbiol., 97:733-745. pdf


114. Ishitsuka, Y., Savage, N., Li, Y., Bergs, A., Kohler, D., Donnelly, R., Nienhaus, U., Fischer, R. & Takeshita, N. (2015) Super-resolution microscopy reveals a dynamic picture of cell polarity maintenance during directional growth.

Science Advances, 1:e1500947. pdf suppl. Material pdf



113. Manck, R., Ishitsuka, Y., Herrero de Vega, S., Takeshita, N., Nienhaus, U.G. & Fischer, R. (2015) Genetic evidence for a microtubule-capture mechanism during polar growth of Aspergillus nidulans.

J. Cell Sci., 128: 3569-3582.  pdf


112. Takeshita, N., Wernet, V., Tsuizaki, M., Grün, N., Hoshi, H., Ohta, A., Fischer, R. & Horiuchi, H. (2015) Transportation of Aspergillus nidulans class III and V chitin synthases to the hyphal tips depends on conventional kinesin.

PLoS One10(5):e0125937pdf


111. Sánchez-León, E., Bowman, B., Seidel, C., Fischer, R., Novick, P. & Riquelme, M. (2015) The Rab GTPase YPT-1 associates with Golgi cistern and Spitzenkörper micro vesicles in Neurospora crassa.

Mol. Microbiol., 95(3):472-490pdf


110. Baumann, S., Grün, N., Takeshita, N., Fischer, R. & Feldbrügge, M. (2015) Live cell imaging of endosomal trafficking in fungi. 


Meth. Mol. Biol., 1270:347-363. pdf



109. Fokina, O., Eipper, J., Winandy, L., Kerzenmacher, S. & Fischer, R. (2015) Improving the performance of a biofuel cell cathode with laccase from Pycnoporus sanguineus.

Biores. Technol., 175, 445-453pdf





108. Requena, N. & Fischer, R. (2014) Braking walls for living in harmony. (insight article)

eLife., 3pdf

107. Pöhlmann, J., Risse, C., Seidel, C., Pohlmann, T., Jakopec, V., Walla, E., Ramrath, P., Takeshita, N., Feldbrügge, M., Fischer, R. & Fleig, U. (2014) The Vip1 inositol polyphosphate kinase family regulates polarized growth and modulates the microtubule cytoskeleton in fungi.

PLoS Genet., 10(9):e1004586pdf



106. Herr, A. & Fischer, R. (2014) Improvement of Aspergillus nidulans penicillin production by targeting AcvA to peroxisomes.

Metab. Eng., 25:131-139. pdf



105. Fischer, R. (2014) Promiscuity breeds diversity: The role of polyketide synthase in natural product biosynthesis4

Chem. Biol., 21:701-702 (preview). pdf

104. Herrero de Vega, S., Takeshita, N. & Fischer, R. (2014) The F-box protein RcyA controls the turnover of the kinesin-7 motor KipA in Aspergillus nidulans. 

Eukaryot. Cell, 13:1085-1094. pdf

103. Takeshita, N., Manck, R., Grün, N., Herrero de Vega, S. & Fischer, R. (2014) Interdependence of the actin and the microtubule cytoskeleton during fungal growth. 

Curr. Opin. Microbiol., 20:34-41.pdf

102Grünbacher, A., Throm, T., Seidel, C., Gutt, B., Röhrig, J., Strunk, T., Vincze, P., Walheim, S., Schimmel, T., Wenzel, W. & Fischer, R. (2014) Six hydrophobins are involved in hydrophobin rodlet formation in Aspergillus nidulans and contribute to hydrophobicity of the spore surface. 

PLoS One, 9(4):e94546. pdf

101. Fetzner, R., Seither, K., Wenderoth, M., Herr, A. & Fischer, R. (2014) The Alternaria alternata transcription factor CmrA controls melanization and spore development. 

Microbiology, 160: 1845-1854. pdf

100Pruß, S., Fetzner, R., Seither, K., Herr, A., Pfeiffer, E., Metzler, M., Lawrence, C.B. & Fischer, R. (2014) On the role of the blue-light receptor WC-1 (LreA) in Alternaria alternata in spore formation and secondary metabolism. 

Appl. Environ. Microbiol., 80(8): 2582-2591pdf




99. Takeshita, N., Mania, D., Herrero de Vega, S., Ishitsuka, Y., Nienhaus, G.U., Podolski, M., Howard, J. & Fischer, R. (2013) The cell end marker TeaA and the microtubule polymerase AlpA contribute to mirotubule guidance at the hyphal tip cortex of Aspergillus nidulans for polarity maintenance. 

J Cell Sci, 126:5400-5411.  pdf


98Hobl, B., Hock, B., Schneck, S., Fischer, R. & Mack, M. (2013) Bacteriophage T7 RNA polymerase-based expression in Pichia pastoris. Protein Expr. Purif. 92(1):100-104.pdf


97. Seidel, C., Moreno-Velasquez, S., Riquelme, M. & Fischer, R. (2013) Neurospora crassa NKIN2, a kinesin-3 motor, transports endosomes and is required for polarized growth. 

Eukaryot. Cell, 12:1020-1032. pdf

96. Röhrig, J., Kastner, C. & Fischer, R. (2013) Light inhibits spore germination through phytochrome in Aspergillus nidulans.

Curr. Genet., 59:55-62. pdf


95. Garzia, A., Etxebeste, O.,  Rodríguez-Romero, J.,  Fischer, R., Espeso, E.A. and Ugalde, U. (2013)  Transcriptional changes in the transition from vegetative cells to asexual development in the model fungus Aspergillus nidulans

Eukaryot. Cell, 12(2):311-321. pdf

94. Kempf, C., Bathe, F. & Fischer, R. (2013) Evidence that two pcl-like cyclins control Cdk9 activity during cell differentiation in Aspergillus nidulans asexual development. 

Eukaryot. Cell, 12(1):23-36. pdf





93. Saha, D., Fetzner, R., Burkhardt, B., Podlech, J., Metzler, M., Dang, H., Lawrence, C. & Fischer, R. (2012) Identification of a polyketide synthase required for alternariol (AOH) and alternariol-9-methyl ether (AME) formation in Alternaria alternata. 

PLoS One, 7(7):e40564.pdf


92. Fischer, R., Kämper, J. & Nick, P. & Requena, N. (2012) Molekulare Mykologie am Karlsruher Institiut für Technologie (KIT). Andrias (Staatl. Museum fuer Naturkunde, Karlsruhe), 19:13-21.



91. Manck, R. & Fischer, R. (2012) Mikroskopie jenseits der Auflösungsgrenze. 

Biologie in Unserer Zeit, 42(4):244-253.pdf


90. Seidel, C., Zekert, N. & Fischer, R. (2012) The tail of the kinesin-3 motor, UncA, is necessary and sufficient to confer specificity for modified microtubules in Aspergillus nidulans. 

PLoS One, 7:e30976pdf


89. Takeshita, N., Diallinas, G. & Fischer, R. (2012) The role of flotillin FloA and stomatin StoA in the maintenance of apical sterol-rich membrane domains (SRDs) and polarity in the filamentous fungus Aspergillus nidulans

Mol. Microbiol., 83(6):1136-1152. pdf


88. Fischer, R. & Rodriguez-Romero, J. (2012) Flavin und lineare Tetrapyrrole als Lichtsensoren in Pilzen. 

Biospektrum, 1.12:19-21. pdf


87. Boef, S., Throm, T., Strunk, T., Hoffmann, M., Seebach, E., Mühlberg, L., T. Gotterbarm, Gutt, B.,  Wenzel, W., Fischer, R. & Richter, W. (2012) Engineering of the hydrophobin DewA to generate surfaces enhancing the adhesion of human cells but not of bacteria. 

Acta Biomat., 8(3):1037-1047. pdf




86. Adamek, M., Overhage, J., Bathe, S., Winter, J., Fischer, R. & Schwartz, T. (2011) Genotyping of environmental and clinical Stenotrophomonas maltophilia isolates and their pathogenic potential. 

PLoS One, 6(11):e27615. pdf


85. Rieder, A., Ladnorg, T., Wöll, C., Obst, U., Fischer, R. & Schwartz, T. (2011) The impact of recombinant fusion-hydrophobin coated surfaces on E coli and natural mixed culture biofilm formation. 

Biofouling, 27:1073-1085.pdf


84. Schunck, T., Herrero de Vega, S. & Fischer, R. (2011) The Aspergillus nidulans CENP-E kinesin KipA is able to form a dimer and move processively along microtubules. 

Curr. Genet., 57:335-341. pdf


83. Ruger-Herreros, C., Rodriguez-Romero, J., Fernandez-Barranco, R., Olmedo, M., Fischer, R., Corrochano, L.M. & Canovas, D. (2011) Regulation of conidiation by light in Aspergillus nidulans

Genetics, 188:809-822. pdf


82. Takeshita, N. & Fischer, R. (2011) On the role of microtubules, cell end markers, and septal microtubule organizing centers on site selection for polar growth in Aspergillus nidulans

Fungal Biol., 115:506-517. pdf


81. Herrero de Vega, S., Takeshita, N. & Fischer, R. (2011) The Aspergillus nidulans CENP-E kinesin motor KipA interacts with the fungal homolog of the centromere-associated protein H at the kinetochore. 

Mol. Microbiol., 80(4):981-994. pdf




80. Mania, M., Hilpert, K., Ruden, S., Fischer, R. & Takeshita, N. (2010) Screening for antifungal peptides and their modes of action in Aspergillus nidulans

Appl. Env. Microbiol., 76:7102-7108. pdf


79. Bayram, Ö., Braus, G., Fischer, R. & Rodriguez-Romero, J. (2010) Spotlight on Aspergillus nidulans photosensory systems. 

Fungal Genet. Biol. 47(11):900-908. pdf


78. Rodriguez-Romero, J., Hedtke, M., Kastner, C., Müller, S. & Fischer, R. (2010) Fungi, hidden in soil or up in the air - Light makes a difference. 

Ann. Rev. Microbiol., 64:585-610. pdf


77. Atoui, A., Thokala, R., Kastner, C., Espeso, E.A., Fischer, R. & Calvo, A.M. (2010) Cross-talk between light and glucose regulation controls morphogenesis and toxin production in Aspergillus nidulans

Fungal Genet. Biol., 47:962-72. pdf


76. Zekert, N., Veith, D. & Fischer, R. (2010) Interaction of the Aspergillus nidulans MTOC component ApsB with gamma-tubulin and evidence for a role of a subclass of peroxisomes in the formation of septal MTOCs. 

Eukaryot. Cell, 9:795-805. pdf


75. Eggenberg, K., Frey, N., Zienicke, B., Siebenbrock, J., Schunck, T., Fischer, R., Bräse, S., Birtalan, E., Nann, T. & Nick, P. (2010) Use of nanoparticles to study and manipulate plant cells. Adv. Biomat., 12:406-412.



74. Bathe, F., Kempf, C., Osmani, S.A., Osmani, A.H., Hettinger, S., Wohlmann, E. & Fischer, R. (2010) Functional characterization of a new member of the Cdk9 family in Aspergillus nidulans

Eukaryot. Cell, 9:1901-1912. pdf




73. Higashitsuji, Y., Herrero, S., Takeshita, N. & Fischer, R. (2009) The cell end marker protein TeaC is involved in growth directionality and septation in Aspergillus nidulans. Eukaryot. Cell, 8:957-967.

72. Zekert, N. & Fischer, R. (2009) The Aspergillus nidulans kinesin-3 UncA motor moves vesicles along a subpopulation of microtubules. Mol. Biol. Cell, 20:673-684.


71. Garzia, A., Etxebeste, O., Fischer, R., Espeso, E.A. & Ugalde, U. (2009) Aspergillus nidulans FlbE is an upstream developmental activator of conidiation functionally associated with the putative transcription factor FlbB. Mol. Microbiol., 71:172-184.

70. Purschwitz, J., Müller, S. & Fischer, R. (2009) Mapping the interaction sites of Aspergillus nidulans phytochrome FphA with the global regulator VeA and the white-collar protein LreB. Mol. Genet. Genom. 281:35-42.



69. Fischer, R. (2008) Sex and poison in the dark. Science, 320:1430-1431. (perspective)

68. Requena, N. & Fischer, R. (2008) chapter "Pilze". Textbook "Mikrobiologie", ed. K. Munck, Thieme, Stuttgart.

67. Purschwitz, J., Müller, S., Kastner, C., Schöser, M., Haas, H., Espeso, E.A., Atoui, A., Calvo, A.M. & Fischer, R. (2008) Functional and physical interaction of blue and red-light sensors in Aspergillus nidulans. Curr. Biol., 18:255-259.

66. Fischer, R., Zekert, N. & Takeshita, N. (2008) Polarized growth in fungi - interplay between the cytoskeleton, positional markers, and membrane domains. Mol. Microbiol., 68(4):813-826. (review)

65. Takeshita, N., Higashitsuji, Y., Konzack, S. & Fischer, R. (2008) Apical sterol-rich membranes are essential for localizing cell end markers that determine growth directionality in the filamentous fungus Aspergillus nidulans. Mol. Biol. Cell, 19(1):339-351.

64. Etxebeste, O., Ni, M., Garzia, A. Kwon, N.-J., Fischer, R., Yu, J.-H., Espeso, E.A. & Ugalde, U. (2008) The bZIP-type transcription factor FlbB controls asexual development in Aspergillus nidulans. Eukaryot. Cell, 7(1):38-48.



63. Takeshita, N., Rolbetzki, A., Vienken, K. & Fischer, R. (2007) The Aspergillus nidulans putative kinase, KfsA (kinase for septation), plays a role in septation and is required for efficient asexual spore formation. Fungal Genet. & Biol., 44:1205-1214.

62. Fischer, R., Takeshita, N. & Doonan, J. (2007) Cytoskeleton, polarized growth and the cell cycle in Aspergillus nidulans. in "The Aspergilli: Genomics, medical applications, biotechnology and research methods", eds. Goldman, G.H. & Osmani, CRC press, p. 223-259. 

61. Enke, C., Zekert, N., Veith, D., Schaaf, C., Konzack, S. & Fischer, R. (2007) The Aspergillus nidulans Dis1/XMAP215 protein AlpA localizes to microtubule plus ends and contributes to growth directionality. Eukaryot. Cell, 6:555-562.

60. Fischer, R. (2007) The role of the cytoskeleton in polarized growth of filamentous fungi. in "The Mycota, Vol VIII, 2nd edition: Biology of the fungal cell", eds. Gow, N.A.R. & Howard, R.J., Springer, Heidelberg, p. 121-135. 

59. Fischer, R. & Veith, D. (2007) The role of microtubules and motors for polarized growth of filamentous fungi. in "Exploitation of fungi", eds. Robson, G.D., van West, P. & Gadd, G.M., Cambridge University Press, pp. 95-116.



58. Purschwitz, J., Müller, S., Kastner, C. & Fischer, R. (2006) Seeing the rainbow - light sensing in fungi. Curr. Opin. Microbiol., 9:566-571.

57. Fischer, R. & Braus, G.H. (2006) Genomsequenz von Schimmelpilzen bringt Sex ans Licht. BIO Spektrum, 3:270-271.

56. Vienken, K. & Fischer, R. (2006) The Zn(II)2Cys6 putative transcription factor NosA controls fruiting body formation in Aspergillus nidulans. Mol. Microbiol., 62(2):544-554.

55. Mander, G., Wang, H., Bodie, E., Wagner, J., Vienken, K., Vinuesa, C., Foster, C., Leeder, A.C., Allen G., Hamill, V., Janssen, G.G., Dunn-Coleman, N., Karos, M., Lemaire, H.G., Subkowski, T., Bollschweiler, C., Turner, G., Nüsslein, B. & Fischer, R. (2006) Laccase as a novel, vesatile reporter gene for filamentous fungi. Appl. Env. Microbiol., 72(7):5020-5026.

54. Kües, U. & Fischer, R. (2006) The Mycota, Vol I, 2nd edition: Growth, Differentiation and Sexuality. Springer, Heidelberg.

53. Fischer, R. & Kües, U. (2006) Asexual sporulation in mycelial fungi. in "The Mycota, Vol I, 2nd. edition: Growth, Differentiation and Sexuality", eds. Kües, U. & Fischer, R., Springer, Heidelberg, pp. 263-292.



52. Nierman, W., A. Pain, M. J. Anderson, J. Wortman, H. S. Kim, J. Arroya, B. Berriman, K. Abe, D. B. Archer, C. Bermejo, J. Bennett, P. Bowyer, D. Chen, M. Collins, R. Coulsen, R. Davies, P. S. Dyer, M. Farman, N. Federova, N. Federova, T. V. Feldblyum, R. Fischer, N. Fosker, A. Fraser, J. L. García, M. J. García, A. Goble, G. H. Goldman, K. Gomi, S. Griffith-Jones, R. Gwilliam, B. Haas, H. Haas, D. Harris, H. Horiuchi, J. Huang, S. Humphrey, J. Jiménez, N. Keller, H. Khouri, K. Kitamoto, T. Kobayashi, S. Konzack, R. Kulkarni, T. Kumagai, A. Lafton, J. P. Latgé, A. Lord, W. Li, A. Lord, C. Lu, W. H. Majoros, G. S. May, B. L. Miller, Y. Mohamoud, M. Molina, M. Monod, I. Mouyna, S. Mulligan, L. Murphy, S. O'Neil, I. Paulsen, M. A. Peñalva, M. Pertea, C. Price, B. L. Pritchard, M. A. Quail, E. Rabbinowitsch, N. Rawlins, M.-A. Rajandream, U. Reichard, H. Renauld, G. D. Robson, S. R. de Córdoba, J. M. Rodríguez-Peña, C. M. Ronning, S. Rutter, S. L. Salzberg, S. Sanchez, J. C. Sánchez-Ferrero, D. Saunders, K. Seeger, R. Squares, S. Squares, T. Takeuchi, F. Tekaia, G. Turner, C. R. Vazquez de Aldana, J. Weidman, O. White, J. Woodward, J.-H. Yu, C. Fraser, J. E. Galagan, K. Asai, M. Machida, N. Hall, B. Barrell, and D. W. Denning (2005) Genomic sequence of the pathogenic and allergenic Aspergillus fumigatus. Nature, 438:1151-1156.

51. Galagan, J. E., S. E. Calvo, C. Cuomo, L.-J. Ma, J. R. Wortman, S. Batzoglou, L. S.-I., M. Bastürkmen, C. C. Spevak, J. Clutterbuck, V. Kapitonov, J. Jurka, C. Scazzocchio, M. Farman, J. Butler, S. Purcell, S. Harris, G. H. Braus, O. Draht, S. Busch, C. d’Enfert, C. Bouchier, G. H. Goldman, D. Bell-Pedersen, S. Griffiths-Jones, J. H. Doonan, J. Yu, K. Vienken, A. Pain, M. Freitag, E. U. Selker, D. B. Archer, M. A. Peñalva, B. R. Oakley, M. Momany, T. Tanaka, T. Kumagai, K. Asai, M. Machida, W. C. Nierman, D. W. Denning, M. Caddick, M. Hynes, M. Paoletti, R. Fischer, B. Miller, P. Dyer, M. S. Sachs, S. A. Osmani, and B. W. Birren (2005) Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae. Nature, 438:1105-1115.

50. Blumenstein, A., Vienken, K., Tasler, R., Purschwitz, J., Veith, D., Frankenberg-Dinkel, N. & Fischer, R. (2005) The Aspergillus nidulans phytochrome FphA represses sexual development in red light. Curr. Biol., 15:1833-1838.

comment: Idnurm, A. & Heitman, J. (2005) Photosensing fungi: Phytochrome in the spotlight. Curr. Biol., 15:R829-R832.

49. Veith, D., Scherr, N., Efimov, V.P. & Fischer, R. (2005) Role of the spindle-pole body protein ApsB and the cortex protein ApsA in microtubule organization and nuclear migration in Aspergillus nidulans. J. Cell Sci., 118:3705-3716. 

48. Konzack, S., Rischitor, E. P., Enke, C. & Fischer, R. (2005) The role of the kinesin motor KipA in microtubule organization and polarized growth of Aspergillus nidulans. Mol. Biol. Cell, 16:497-506.

47. Vienken, K., Scherer, M. & Fischer, R. (2005) The Zn(II)2Cys6 transcription factor RosA (repressor of sexual development) triggers early developmental decisions in the filamentous fungus Aspergillus nidulans. Genetics, 169(2):619-630.



46. Toews, M.W., Warmbold, J., Konzack, S., Rischitor, E.P., Veith, D., Vinuesa, C., Vienken, K., Wei, H. & Fischer, R. (2004) Establishment of mRFP1 as a fluorescent marker in Aspergillus nidulans and construction of expression vectors for high-throughput protein tagging using recombination in vitro (GATEWAY). Curr. Genet., 45:883-889.

45. Rischitor, E.P., Konzack, S. & Fischer, R. (2004) The Kip3-like kinesin KipB moves along microtubules and determines spindle position during synchronized mitoses in Aspergillus nidulans hyphae. Eukaryot. Cell, 3(3):632-645.

44. Xiang, X. & Fischer, R. (2004) Nuclear migration and positioning in filamentous fungi. Fungal Genet. & Biol., 41, 411-419.

43. Breuninger, M., Trujillo, C.G., Serrano, E., Fischer, R. & Requena, N. (2004) Different nitrogen sources modulate activity but not expression of glutamine synthetase in arbuscular mycorrhizal fungi. Fungal Genet. & Biol., 41, 542-552.

42. Wei, H., Vienken K., Weber, R., Bunting, S., Requena, N. & Fischer, R. (2004) A putative high affinity hexose transporter, hxtA, of Aspergillus nidulans is induced in vegetative hyphae upon starvation and in ascogenous hyphae during cleistothecium formation. Fungal Genet. & Biol., 41, 148-156.



41. Koch, K., Suelmann, R. & Fischer, R. (2003) Deletion of mdmA impairs mitochondrial distribution and morphology in Aspergillus nidulans. Cell Mot. Cytoskel., 55, 114-124.

40. Riquelme, M., Fischer, R. & Bartnicki-Garcia, S. (2003) Apical growth and mitosis in Aspergillus nidulans do not compete for the same microtubule resources. Protoplasma, 222, 211-215.

39. Wei, H., Requena, N. & Fischer, R. (2003) The MAPKK-kinase SteC regulates conidiophore morphology and is essential for heterokaryon formation and sexual development in the homothallic fungus Aspergillus nidulans. Mol. Microbiol., 47(6), 1577-1588.

38. Kües, U. & Fischer, R. (2003) Fungal development. Chapter in "Genomics of Plants and Fungi", ed. Prade, R.A. and Bohnert, H.J., 41-118.

37. Zhang, J., Li, S., Fischer, R. & Xiang, X. (2003) The accumulation of cytoplasmic dynein and dynactin at microtubule plus-ends is kinesin dependent in Aspergillus nidulans. Mol. Biol. Cell., 14, 1479-1488.



36. Scherer, M., Wei, H. & Fischer, R. (2002) Aspergillus nidulans catalase-peroxidase (cpeA) is transcriptionally induced during sexual development through the APSES-transcription factor StuA. Eukaryot. Cell, 1, 725-735.

35. Schier, N. & Fischer, R. (2002) The Aspergillus nidulans cyclin PclA accumulates in the nucleus and interacts with the central cell cycle regulator NimXcdc2. FEBS Lett., 523(1-3), 143-146.

34. Fischer, R. (2002) Conidiation in Aspergillus nidulans. Chapter in "Molecular Biology of Fungal Development", ed. Osiewacz, H., Marcel Decker, New York, p. 59-86.

33. Scherer, M., Schier, N. & Fischer, R. (2002) Achtung: Schimmelpilze im Labor, BIOforum, 3:120-123.

32. Mertens, D. & Fischer, R. (2002) Kinesine: Motorproteine der Zelle, Biologie in Unserer Zeit, 5, 311-318.

31. Herzberg, M., Fischer, R. & Tietze, A. (2002) Conflicting results obtained by RAPD-PCR and large subunit rDNA sequences in determining and comparing yeast strains isolated from flowers, a comparison of two methods. Int. J. System. Evol. Microbiol., 1423-1433.



30. Wei, H., Scherer, M., Singh, A., Liese, R. & Fischer, R. (2001) Aspergillus nidulans alpha-1,3-glucanase (mutanase), mutA, is expressed during sexual development and mobilises mutan. Fungal Genet. & Biol., 34(3), 217-227. (with cover)

29. Geissenhöner, A., Sievers, N., Brock, M. & Fischer, R. (2001) Aspergillus nidulans DigA, a potential homologue of Saccharomyces cerevisiae Pep3(Vps18)(vacuolar protein sorting), is required for nuclear migration, mitochondrial morphology and polarized growth. Mol. Genet. Genomics, 266, 672-685.

28. Requena, N., Alberti-Segui, C., Winzenburg, E., Horn, C., Schliwa, M., Liese, R., Philippsen, P. & Fischer, R. (2001) Conventional kinesin of Aspergillus nidulans destabilizes microtubules and thus controls nuclear distribution. Mol. Microbiol., 42(1), 121-133.

27. Schier, N., Liese, R. & Fischer, R. (2001) A pcl-like cyclin of Aspergillus nidulans is transcriptionally activated by developmental regulators and is involved in sporulation. Mol. Cell. Biol., 21(12), 4075-4088. (with cover)

26. Scherer, M. & Fischer, R. (2001) Laccase III of Aspergillus nidulans localizes to the growing hyphal tip. FEMS Microbiol. Lett., 199, 207-213.


2000 and older

25. Suelmann, R. & Fischer, R. (2000) Mitochondrial morphology and movement are dependent on an intact actin cytoskeleton in Aspergillus nidulans. Cell Mot. Cytoskel., 45(1), 42-50.

24. Suelmann, R. & Fischer, R. (2000) Nuclear migration in fungi – Different motors at work. Res. Microbiol., 151:247-254.

23. Requena, N. & Fischer, R. (2000) Pilze. Textbook "Grundstudium Biologie: Mikrobiologie", ed. K. Munck, Spektrum Verlag, Kapitel V, p. 1-28.

22. Brock, M., Fischer, R., Linder, D. & Buckel, W. (2000) Methylcitrate synthase from Aspergillus nidulans: Implications for propionate as antifungal agent. Mol. Microbiol. 35, 961-973.

21. Sievers, N., Bertsch, E. & Fischer, R. (1999) Isolation of nuclear migration mutants of Aspergillus nidulans using GFP expressing strains. Mycol. Res., 103(8), 961-966.

20. Fischer, R. (1999) Nuclear movement in filamentous fungi. FEMS Microbiol. Rev., 23, 39-68.

19. Fischer, R. (1999) Gibt es ein Cytoskelett in Prokaryoten? Biologie in Unserer Zeit, 5, 278-285.

18. Karos, M. & Fischer, R. (1999) Molecular characterization of HymA, an evolutionarily highly conserved and highly expressed protein of Aspergillus nidulans. Mol. Gen. Genet., 260, 510-521.

17. Suelmann, R., Sievers, N., Galetzka, D., Robertson, L., Timberlake, W.E. & Fischer R. (1998) Nuclear traffic chaos in hyphae of apsB mutants of Aspergillus nidulans: Molecular characterization of apsB and in vivo observations of nuclear behaviour. Mol. Microbiol., 30(4), 831-842.

16. Scherer, M. & Fischer, R. (1998) Purification and characterization of laccase II of Aspergillus nidulans. Arch. Microbiol., 170, 78-84.

15. Fischer, R. (1998) Isolation of mutants, a key for the analysis of complex pathways and for strain improvement. in Microbes: For health, wealth and sustainable environment, editor A. K. Varma, MPH, New Delhi, Indien. pp. 739-751.

14. Krüger, M. & Fischer, R. (1998) Integrity of a Zn-finger like domain in SamB is crucial for morphogenesis in ascomycetous fungi. EMBO J., 17(1), 204-214.

13. Suelmann, R. & Fischer R. (1997) Nuclear traffic in fungal hyphae: In vivo study of nuclear migration and positioning in Aspergillus nidulans. Mol. Microbiol., 25(4), 757-769. (with cover)

12. Krüger, M., Sievers, N. & Fischer, R. (1997) Molekularbiologie der Sporenträgerentwicklung des Schimmelpilzes Aspergillus nidulans. Biologie in Unserer Zeit, 6, 375-382.

11. Sievers, N., Krüger, M. & Fischer, R. (1997) Das Experiment: Kreuzung von Aspergillus nidulans. Biologie in Unserer Zeit, 6, 383-388.

10. Krüger, M. & Fischer, R. (1996) Isolation of two apsA suppressor strains in Aspergillus nidulans. Genetics, 144, 533-540.

9. Karos, M. & Fischer, R. (1996) hymA (hypha-like metulae), a new developmental mutant of Aspergillus nidulans. Microbiology, 142, 3211-3218. (with cover)

8. Fischer R. & Timberlake W.E. (1995) Aspergillus nidulans apsA (anucleate primary sterigmata) encodes a coiled-coil protein required for nuclear positioning and for completion of asexual development. J. Cell Biol., 128(4), 485-498. (with cover)



7. Gärtner P., Eckert A., Fischer R., Linder D., Fuchs G. & Thauer R.K. (1993) Purification and properties of N5-Methyltretrahydomethanopterin:coenzyme M methyltransferase from Methanobacterium thermoautotrophicum. Eur. J. Biochem., 213, 537-545.

6. Thauer R.K., Hedderich R. & Fischer R. (1993) Reactions and enzymes involved in methanogenesis from CO2 and H2. in Ferry J.G. (Ed): Methanogenesis. Chapman & Hall, New York. pp. 209-252.

5. Fischer R., Gärtner P., Yeliseev A. & Thauer R.K. (1992) N-Methyltetrahydromethanopterin:coenzyme M methyltransferase in methanogenic bacteria is a membrane protein. Arch. Microbiol., 158, 208-217.

4. Fischer R. & Thauer R.K. (1990) Ferredoxin-dependent methane formation from acetate in cell extracts of Methanosarcina barkeri (strain MS). FEBS Letters, 269, 368-372.

3. Fischer R. & Thauer R.K. (1990) Methanogenesis from acetate in cell extracts of Methanosarcina barkeri: Isotope exchange between CO and the carbonyl group of acetyl-CoA, and the role of H2. Arch. Microbiol., 153, 156-162.

2. Fischer R. & Thauer R.K. (1989) Methyltetrahydromethanopterin as an intermediate in methanogenesis from acetate in Methanosarcina barkeri. Arch. Microbiol., 151, 459-465.

1. Fischer R. & Thauer R.K. (1988) Methane formation from acetyl-phosphate in cell extracts of Methanosarcina barkeri: Dependence of the reaction on coenzyme A. FEBS Letters, 228, 249-253.