2024
Wimmi S, Balinovic A, Brianceau C, Pintor K, Vielhauer J, Turkowyd B, Helbig C, Fleck M, Langenfeld K, Kahnt J, Glatter T, Endesfelder U & Diepold A (2024) Cytosolic sorting platform complexes shuttle type III secretion system effectors to the injectisome in Yersinia enterocolitica. Nat. Microbiol. 9: 185–199
Jakob S, Steinchen W, Hanßmann J, Rosum J, Langenfeld K, Osorio-Valeriano M, Steube N, Giammarinaro PI, Hochberg GKA, Glatter T, Bange G, Diepold A & Thanbichler M (2024) The virulence regulator VirB from Shigella flexneri uses a CTP-dependent switch mechanism to activate gene expression. Nat. Commun. 15: 318
Ermoli F, Spahn C, Glatter T & Diepold A (2024) Yersinia actively downregulates type III secretion and adhesion at higher cell densities. under Rev. bioRxiv
Wimmi S, Fleck M, Helbig C, Brianceau C, Langenfeld K, Szymanski WG, Angelidou G, Glatter T & Diepold A (2024) Pilotins are mobile T3SS components involved in assembly and substrate specificity of the bacterial type III secretion system. Mol. Microbiol. 121: 304–323
Diepold A (2024) Defining Assembly Pathways by Fluorescence Microscopy. In Methods in Molecular Biology pp 383–394.
Lampaki D, Diepold A & Glatter T (2024) In-Depth Quantitative Proteomics Analysis of the Pseudomonas aeruginosa Secretome. In Methods in Molecular Biology pp 197–211.
2022-2023
Nikolić I, Glatter T, Ranković T, Berić T, Stanković S & Diepold A (2023) Repertoire and abundance of secreted virulence factors shape the pathogenic capacity of Pseudomonas syringae pv. aptata. Front. Microbiol. 14:
Carsten A, Rudolph M, Weihs T, Schmidt R, Jansen I, Wurm CA, Diepold A, Failla AV, Wolters M & Aepfelbacher M (2023) MINFLUX imaging of a bacterial molecular machine at nanometer resolution. Methods Appl. Fluoresc. 11: 015004
Schott S, Scheuer R, Ermoli F, Glatter T, Evguenieva-Hackenberg E & Diepold A (2023) A ParDE toxin–antitoxin system is responsible for the maintenance of the Yersinia virulence plasmid but not for type III secretion-associated growth inhibition. Front. Cell. Infect. Microbiol. 13:
Prindle JR, Wang Y, Rocha JM, Diepold A & Gahlmann A (2022) Distinct Cytosolic Complexes Containing the Type III Secretion System ATPase Resolved by Three-Dimensional Single-Molecule Tracking in Live Yersinia enterocolitica. Microbiol. Spectr. 10:
Unni R, Pintor KL, Diepold A & Unterweger D (2022) Presence and absence of type VI secretion systems in bacteria. Microbiology 168:
Gurung JM, Amer AAA, Chen S, Diepold A & Francis MS (2022) Type III secretion by Yersinia pseudotuberculosis is reliant upon an authentic N‐terminal YscX secretor domain. Mol. Microbiol. 117: 886–906
Lindner F & Diepold A (2022) Optogenetics in bacteria – applications and opportunities. FEMS Microbiol. Rev. 46: fuab055
2020-2021
Wimmi S, Lindner F & Diepold A (2021) Gezielte Injektion von Effektoren durch Kontrolle der Proteindynamik. BIOspektrum 27: 697–700
Berger C, Ravelli RBG, López-Iglesias C, Kudryashev M, Diepold A & Peters PJ (2021) Structure of the Yersinia injectisome in intracellular host cell phagosomes revealed by cryo FIB electron tomography. J. Struct. Biol. 213: 107701
Milne-Davies B, Wimmi S & Diepold A (2021) Adaptivity and dynamics in type III secretion systems. Mol. Microbiol. 115: 395–411
Wimmi S, Balinovic A, Jeckel H, Selinger L, Lampaki D, Eisemann E, Meuskens I, Linke D, Drescher K, Endesfelder U & Diepold A (2021) Dynamic relocalization of cytosolic type III secretion system components prevents premature protein secretion at low external pH. Nat. Commun. 12: 1625
Lampaki D, Diepold A & Glatter T (2020) A Serial Sample Processing Strategy with Improved Performance for in-Depth Quantitative Analysis of Type III Secretion Events in Pseudomonas aeruginosa. J. Proteome Res. 19: 543–553
Lindner F, Milne-Davies B, Langenfeld K, Stiewe T & Diepold A (2020) LITESEC-T3SS - Light-controlled protein delivery into eukaryotic cells with high spatial and temporal resolution. Nat. Commun. 11: 2381
Lindner F, Gahlmann A & Diepold A (2020) Optogenetic control of protein translocation - Protein secretion and translocation into eukaryotic cells with high spatial and temporal resolution by light-controlled activation of the bacterial type III secretion system. : PCT/EP2020/058769
Wagner S & Diepold A (2020) A Unified Nomenclature for Injectisome-Type Type III Secretion Systems. In Current topics in microbiology and immunology pp 427: 1–10.
2016-2019
Milne-Davies B, Helbig C, Wimmi S, Cheng DWC, Paczia N & Diepold A (2019) Life After Secretion—Yersinia enterocolitica Rapidly Toggles Effector Secretion and Can Resume Cell Division in Response to Changing External Conditions. Front. Microbiol. 10: 2128
Tseytin I, Mitrovic B, David N, Langenfeld K, Zarivach R, Diepold A & Sal-Man N (2019) The Role of the Small Export Apparatus Protein, SctS, in the Activity of the Type III Secretion System. Front. Microbiol. 10: 2551
Baker AE, Webster SS, Diepold A, Kuchma SL, Bordeleau E, Armitage JP & O’Toole GA (2019) Flagellar Stators Stimulate c-di-GMP Production by Pseudomonas aeruginosa. J. Bacteriol. 201: e00741-18
Diepold A (2019) Assembly and Post-assembly Turnover and Dynamics in the Type III Secretion System. In Current topics in microbiology and immunology pp 427:35–66.
Nauth T, Huschka F, Schweizer M, Bosse JB, Diepold A, Failla AV, Steffen A, Stradal TEB, Wolters M & Aepfelbacher M (2018) Visualization of translocons in Yersinia type III protein secretion machines during host cell infection. PLOS Pathog. 14: e1007527
Rocha JM, Richardson CJ, Zhang M, Darch CM, Cai E, Diepold A & Gahlmann A (2018) Single-molecule tracking in live: Yersinia enterocolitica reveals distinct cytosolic complexes of injectisome subunits. Integr. Biol. (United Kingdom) 10: 502–515
Morgan JM, Duncan MC, Johnson KS, Diepold A, Lam H, Dupzyk AJ, Martin LR, Wong WR, Armitage JP, Linington RG & Auerbuch V (2017) Piericidin A1 Blocks Yersinia Ysc Type III Secretion System Needle Assembly. mSphere 2: e00030-17
Zoued A & Diepold A (2017) Defining Assembly Pathways by Fluorescence Microscopy. In Methods in molecular biology (Clifton, N.J.), Journet L & Cascales E (eds) pp 289–298.
Diepold A, Sezgin E, Huseyin M, Mortimer T, Eggeling C & Armitage JP (2017) A dynamic and adaptive network of cytosolic interactions governs protein export by the T3SS injectisome. Nat. Commun. 8: 15940
Baker AE, Diepold A, Kuchma SL, Scott JE, Ha DG, Orazi G, Armitage JP & O’Toole GA (2016) PilZ Domain Protein FlgZ Mediates Cyclic Di-GMP-Dependent Swarming Motility Control in Pseudomonas aeruginosa. J. Bacteriol. 198: 1837–1846
2013-2015
Diepold A & Armitage JP (2015) Type III secretion systems: the bacterial flagellum and the injectisome. Philos. Trans. R. Soc. B Biol. Sci. 370: 20150020
Gerc AJ, Diepold A, Trunk K, Porter M, Rickman C, Armitage JP, Stanley-Wall NRNR & Coulthurst SJ (2015) Visualization of the Serratia Type VI Secretion System Reveals Unprovoked Attacks and Dynamic Assembly. Cell Rep. 12: 2131–2142
Kudryashev M, Diepold A, Amstutz M, Armitage JP, Stahlberg H & Cornelis GR (2015) Yersinia enterocolitica type III secretion injectisomes form regularly spaced clusters, which incorporate new machines upon activation. Mol. Microbiol. 95: 875–884
Diepold A, Kudryashev M, Delalez NJ, Berry RM & Armitage JP (2015) Composition, Formation, and Regulation of the Cytosolic C-ring, a Dynamic Component of the Type III Secretion Injectisome. PLOS Biol. 13: e1002039
Diepold A & Wagner S (2014) Assembly of the bacterial type III secretion machinery. FEMS Microbiol. Rev. 38: 802–22
Kudryashev M, Stenta M, Schmelz S, Amstutz M, Wiesand U, Castaño-Díez D, Degiacomi MT, Münnich S, Bleck CK, Kowal J, Diepold A, Heinz DW, Dal Peraro M, Cornelis GR & Stahlberg H (2013) In situ structural analysis of the Yersinia enterocolitica injectisome. Elife 2: e00792
2007-2012
Diepold A, Wiesand U, Amstutz M & Cornelis GR (2012) Assembly of the Yersinia injectisome: the missing pieces. Mol. Microbiol. 85: 878–92
Diepold A, Wiesand U & Cornelis GR (2011) The assembly of the export apparatus (YscR,S,T,U,V) of the Yersinia type III secretion apparatus occurs independently of other structural components and involves the formation of an YscV oligomer. Mol. Microbiol. 82: 502–14
Diepold A, Amstutz M, Abel S, Sorg I, Jenal U & Cornelis GR (2010) Deciphering the assembly of the Yersinia type III secretion injectisome. EMBO J. 29: 1928–40
Diepold A, Li G, Lennarz WJ, Nürnberger T & Brunner F (2007) The Arabidopsis AtPNG1 gene encodes a peptide: N-glycanase. Plant J. 52: 94–104